metabolomics相关论文
Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transp
Omics data address key issues in liver transplantation (LT) as the most effective therapeutic means for end-stage liver ......
Pathological Change of Chronic Hepatitis B Patients with Different Tongue Coatings by Circular Multi
Objective:To compare the circular pathological changes of chronic hepatitis B (CHB) patients according to the tongue dia......
Transcriptome sequencing and metabolome analysis reveal the mechanism of Shuanghua Baihe Tablet in t
Oral mucositis (OM) caused by cancer therapy is the most common adverse reaction in the radiotherapy of head and neck tu......
Integrating 16S sequencing and metabolomics study on anti-rheumatic mechanisms against collagen-indu
Wantong Jingu Tablet(WJT),a mixture of traditional Chinese medicine,was reported to relieve the symptoms of rheumatoid a......
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells du
Japanese encephalitis virus (JEV) is a leading cause of viral encephalitis in endemic regions of Asia.The neurotropism o......
Background:Metabolomic approaches, which include the study of low molecular weight molecules, are an emerging-omics tech......
Comparisons of Metabolic Profiles for Carbohydrates,Amino Acids,Lipids,Fragrance and Flavones During
We used a widely targeted metabolomics approach to examine the metabolic changes in three pedigreed indica cultivars (Me......
Metabolomic characteristics of spontaneously hypertensive rats under chronic stress and the treatmen
Objective:Numerous studies have demonstrated the close relationship between chronic stress and blood pressure (BP).Hyper......
创伤性颅脑损伤(TBI)虽然有明确的致伤因素,但复杂的原发伤叠加患者自身存在的损伤易感性因素,发生多种病理生理进程,产生了海量生物......
探讨复合茶的降脂作用,为茶叶的降脂机理及复合茶开发和应用提供理论支撑.SPF级雄性KM小鼠随机分为模型对照组(NK)、阳性对照组(YK......
Integration of metabolomics and transcriptomics revealed the biosynthetic mechanism of anti-parasiti
The fermentation broth of Salinivibrio proteolyticus strain YCSC6 shows potent anti-parasitic activity against Uronema m......
Metabolomics provide insights into the endogenous mechanism of strobilation in the scyphozoan jellyf
Strobilation is a well-organized metamorphosis process in scyphozoan jellyfish, through which the benthic polyp develops......
Continuous docetaxel (DTX) treatment of non-small cell lung cancer induces development of drug resistance,but the mechan......
A herbal prescription in traditional Chinese medicine(TCM)has great complexity,with multiple compo-nents and multiple ta......
Stearoyl-CoA desaturase 1 inhibitor supplemented with gemcitabine treatment reduces the viability an
Objective::Pancreatic cancer (PC) is an aggressive cancer with ineffective treatment. Inhibition of stearoyl-CoA desatur......
急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS)是以顽固性低氧血症为特征、严重威胁患者生命的肺部疾病。代谢组学是对生物或细胞内小分......
急性呼吸窘迫综合征(ARDS)在临床具有发病率高、病死率高的特点,是导致重症患者死亡的重要因素之一。探索ARDS早期预警、严重程度及预......
糖尿病视网膜病变(DR)是糖尿病严重并发症之一,发病机制复杂,目前尚未完全阐明。代谢改变与表型关系密切,代谢组学分析可以提示细胞、......
Liver metabolomics study reveals protective function of Phyllanthus urinaria against CCl4-induced li
Phyllanthus Urinaria L.(PUL) is a traditional Chinese medicine used to treat hepatic and renal disorders.However,the mec......
1H NMR-based metabolomics approach to investigating the renal protective effects of Genipin in diabe
Diabetic nephropathy is one of the various complications of diabetes mellitus,affecting patients for lifetime.Earlier st......
A novel approach based on metabolomics coupled with network pharmacology to explain the effect mecha
Danggui Buxue Tang (DBT) is a famous Chinese medicinal decoction.Mechanism of DBT action is wide ranging and unclear.Exp......
Cimicifuga heracleifolia is therapeutically similar to black cohosh in relieving menopausal symptoms
In the market of botanical dietary supplements,Cimicifuga heracleifolia (CH) has always been considered as an adulterate......
UHPLC-LTQ-Orbitrap-based metabolomics coupled with metabolomics pathway analysis method for explorin
Kudiezi injection has been used extensively in the treatment of cerebrovascular and cardiovascular diseases.However,its ......
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UPLC/ESI-QTOF-MS-based metabolomics survey on the toxicity of triptolide and detoxication of licoric
Triptolide (TP) from Tripterygium wilfordii has been demonstrated to possess anti-inflammatory,immunosuppressive,and ant......
Osthole attenuates pulmonary arterial hypertension by the regulation of sphingosine 1-phosphate in r
Osthole is observed to have the capacity to treat pulmonary arterial hypertension (PAH) in rats,but molecular mechanism ......
Novel chinmedomics strategy for discovering effective constituents from ShenQiWan acting on ShenYang
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Metabolomics and its application in the treatment of coronary heart disease with traditional Chinese
Traditional Chinese Medicine (TCM) is the treasure of Chinese Nation and gained the gradual acceptance of the internatio......
Metabolomics: a novel approach to identify potential diagnostic biomarkers and pathogenesis in Alzhe
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Stearoyl-CoA desaturase 1 inhibitor supplemented with gemcitabine treatment reduces the viability an
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Prediction of metabolizable energy from plasma biomarkers in nursery pigs using a metabolomic approa
Conventional methods of requirement assessment or feedstuff nutrient evaluation,which provide an estimate for the mean v......
Intestinal microbial communities play a central role in nutrient and energy cycling of host.The swimming crab has a clos......
Changes in the water-soluble metabolites of L.helveticusH9 during fermentation were analysed by ultra performance liquid......
Integrated isotope-assisted metabolomics and 15C metabolic flux analysis reveals metabolic flux redi
Aspergillus niger is widely used for enzyme production and achievement of high enzyme production depends on the comprehe......
Garcinia is a genus in the Clusiaceae family with a number of well-known medicinal plants from southern China, many with......
This study identified differences in plasma metabolites among three groups of dairy cows:type Ⅰ ketotic (K1) ,type Ⅱ k......
This study identified differences in plasma metabolites among three groups of dairy cows:type Ⅰ ketotic (K1),type Ⅱ ke......
The underlying mechanism of allelopathic interaction between rice secondary metabolites and Myxococc
Allelopathy results from the interactions between rice and its rhizosphere microbes.In this study,the contents of phenol......
Molecular mechanisms underlying salt tolerance differences in barley and rice revealed by multi-omic
Salt stress is one of the major abiotic stresses limiting crops production globally.Barley and rice differ greatly in th......
Metaboliteprofilingofurineextractsfrompatientswithcolorectal cancerbasedonNMRandPatter
Introduction ColorectalCancer(CRC)isoneofthemostprevalenttypesofcancerdeathworldwide.ProtonMagneticresonance Spectroscop......
Serum Metabolomics Analysis for Early Screening of Esophageal Squamous Cell Carcinoma in High-incide
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Comparative metabolomics anlaysis between two traditional Chinese medicine extracts used for treatin
Objective Macranthoidin B is a triterpenoid saponin exaction from Flos Lonicerae(Shanyinhua in Chinese),which was tradit......
Metabolite profiling of urine extracts from patients with esophageal cancer based on NMR and Pattern
Motivation Esophageal cancer(EC)is one of the most commen malignant tumors with a high prevalence of cancer-related morb......
Metabolomicanalysiswasperformedtodeterminethemetabolomicsignatureofosteonecrosisofthefemoralhead(ONFH),andtheunderlyingr......
GC-MS metabolomics analysis of the biological effects of radiation in multislice computed tomography
Purpose To identify patterns of metabolic changes and plasma biomarkers associated with low dose ionizing radiation(LDR)......
Objective Metabolites and somatic mutations involved in the EGFR-TKI efficacy remains unclear in the first-line non-smal......